Polyglycan® is the primary product for joint injections in my equine practice since 2006.
Polyglycan® has been administered extensively to horses competing in a variety of disciplines. This population includes professional rodeo horses, cutting horses, reining horses, working cow horses, racehorses, and horses in the English disciplines ... We’ve used over 50,000 mL of Polyglycan® in our practice giving us a high level of comfort and confidence in its applications. To date there have been no adverse events to be reported by our clients or our practice. Through my peer group I have not had conversations to suggest that their experience has been different.
Chris Morrow, DVM
Mobile Veterinary Practice, Amarillo, TX
Polyglycan is administered intra-articularly and intravenously in my practice. I administer Polyglycan intra-articularly during and after joint surgery, and the horses are administered Polyglycan weekly for, at least, 4 weeks after surgery
"Polyglycan (hyaluron, sodium chondroitin, N-acetyl-D-glucosamine) is administered in my practice. I administer Polyglycan during and after joint surgery (arthroscopy or arthrotomy), and the horses are administered Polyglycan weekly for, at least, 4 weeks after surgery, if financially feasible. A large part of my practice is arthroscopic removal of OCD lesions and chip fractures in Thoroughbred yearlings. The vast majority of these joints do not have radiographic or clinical signs of osteoarthritis prior to surgery. I routinely perform post-operative films within 30 days after surgery, and a large number of these horses have radiographs taken for use at auction several months after surgery. I have not observed osteophyte formation after administering Polyglycan in these cases for the past 9 years.
In my opinion, there is decreased joint morbidity in the cases where Polyglycan is administered after surgery versus the cases that do not receive Polyglycan. I also observe decreased joint morbidity and quicker resolution of effusion in the race horses and yearlings that have clinical and radiographic evidence of osteoarthritis prior to surgery."
C.R. Johnson, DVM, MS, DACVS
Equine Surgical Services, Versailles, KY
I use Polyglycan exclusively (other than biologics) in joint therapy. In other words, Polyglycan is my "go to" medication.
I have used Polyglycan since 2010. Since then our clinic has used over 70,000 doses in both post-surgical and treatment of typical inflammatory conditions of the joint. In my experience, I have very good to acceptable outcomes using Polyglycan in routine joint therapy. Additionally, we have not experienced the occasional joint flair seen in other products. We have not had any problems with any type of proliferative arthritic conditions. Currently, I use Polyglycan exclusively (other than biologics) in joint therapy. In other words, Polyglycan is my "go to" medication.
Robert W. Brusie, DVM, Diplomat ACVS
Palm Beach Equine Clinic, Wellington, FL
I have continued to use Polyglycan as a standard postoperative parenteral treatment as well for essentially all of my orthopedics.
"I began using Polyglycan in a clinical setting over 10 years ago, initially as a post-surgical lavage following arthroscopic surgery. Soon afterward I began routine administration on a weekly or bi-weekly basis on athletes with musculoskeletal maintenance issues as well as young developing horses with developmental orthopedic disease. I have continued to use Polyglycan as a standard postoperative treatment as well for essentially all of my orthopedics. I have encountered no adverse effects from either route of administration of Polyglycan.
In addition to using Polyglycan in racing athletes and sport horses, I routinely recommend its use in weanlings and yearlings with synovitis and joint effusions that are the result of osteochondrosis lesions. I also frequently administer Polyglycan in foals undergoing treatment for septic arthritis. I have not experienced any adverse reactions with the use of Polyglycan."
Robert J. Hunt, DVM, MS, Diplomate, ACVS
Hagyard Equine Medical Institute, Lexington, KY
"In the treatment efficacy portion, joints of Polyglycan® treated horses had fewer microscopic articular cartilage abnormalities as well.
There has apparently been no report of any clinical or radiographic consequences in this location with clinical use in the horse.”
C. Wayne McIlwraith, BVSc, PhD, DACVS, DACVSMR
Orthopaedic Research Center, CSU
David D. Frisbie, PhD, DACVS, DACVSMR
Orthopaedic Research Center, CSU
Excerpts from a summary document prepared by the Co-Principal Investigators of a CSU study in response to concerns raised from their paper that the use of intravenous administration of Polyglycan® might cause harm.